Spiegelmer-Based Sandwich Assay for Cardiac Troponin I Detection
نویسندگان
چکیده
منابع مشابه
Analytical performance of the i-STAT cardiac troponin I assay.
BACKGROUND This study determines the analytical characteristics of the i-STAT cardiac troponin I assay (cTnI; i-STAT, Princeton, NJ), a 10-min POC assay, designed to be performed at the bedside. METHODS Three different hospitals participated in a patient specimen and analytical validation study (n=186) for the i-STAT cTnI assay carried out in real time. A total of 186 whole blood specimens (l...
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I read with great interest the article of Kavsak et al. (1 ) on the utility of a next-generation high-sensitivity Beckman Coulter cardiac troponin I (cTnI) assay with a 20% CV at 2.95 ng/L. This approach demonstrated a higher diagnostic sensitivity (81% vs 62%) for myocardial injury with a changing pattern of cTnI values, compared with the AccuTnI assay cleared by the US Food and Drug Administr...
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Cardiac troponin is the marker of choice for evaluating myocardial injury (1 ). High-sensitivity assays improve analytical detection limits, thereby allowing concentrations to be measured in the majority of healthy individuals. This capability allows an assessment of biologic variation (BV) to determine what constitutes an important change in the cardiac troponin concentration, a critical metri...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2020
ISSN: 1422-0067
DOI: 10.3390/ijms21144963